Discovery Solutions

Integrated Drug Discovery (IDD)

Aral Research offers integrated drug discovery solutions designed to accelerate programs from hit identification to lead optimization and preclinical candidate support. Our multidisciplinary scientific approach combines medicinal chemistry, synthetic chemistry, biology collaborations, DMPK support, and analytical sciences to enable efficient and data-driven decision-making throughout the discovery journey. Our IDD program models are ideal for clients who are planning a comprehensive strategy with a staged process which can be executed under a Master Services Agreement. Integrated Discovery-to-Scale Chemistry Platform for biotech companies, startups, and pharma clients looking for: 
all under one integrated partnership model.

Project Initiation Stage (Hit Identification)

Establish progression path

Hit to Lead

Identify patentable lead compounds

SAR development

Establish in vivo activity with patentable leads

Lead optimization stage

Identify preclinical compounds

Desirable PK and toxicological profile

Patent filing

Development

Preclinical Evaluation (Non GLP). Finalize preclinical compound

Establish PK-PD correlation and toxicology in two species

API process chemistry

Integrated Discovery-to-Scale Platform

The Aral + Khodiyar integrated model seamlessly connects scientific project execution with large-scale GMP manufacturing — from first hit to commercial API supply.

Integrated Chemistry Flow :

GMP & GLP Certified Manufacturing Capability

GMP-certified manufacturing plant

GLP-certified R&D tech transfer capability

Large Scale Manufacturing Capability

Reactor capacity: 250 L to 10,000 L

Temperature range: -70°C to +280°C

Pilot plant capability

Kilo lab support

Multi-purpose manufacturing

Equipment & Infrastructure Strength

Glass-lined reactors

SS reactors

Agitated Nutsche Filter Dryer.

Centrifuges

Vacuum tray dryers

Sparkler filters

Hydrogenation setup

Kilo lab

Pilot plant

Process Development & Scale-Up Expertise

Process optimization

Route scalability

Cost optimization

Tech transfer

Pilot-scale validation

Commercial manufacturing readiness

Chemistry Technology Expertise

Amidation

Grignard chemistry

Halogenation

Oxidation

Cyclization

Condensation

Esterification

Rearrangement

High vacuum distillation

Multi-step synthesis

Analytical Capabilities

HPLC / UPLC analysis

LCMS / HRMS characterization

NMR characterization (¹H including ¹³C NMR, DEPT APT, 19F, 31P NMR, 29Si NMR, 2D NMR)

GC-HS Analysis

GC-HS Analysis

GC-analysis

GC-MS Analysis

Karl Fischer (KF) moisture analysis

IR spectroscopy

UV-Visible spectroscopy

ICP-OES/ICP-MS Analysis

XRD Analysis

Purity and assay determination

Residual solvent analysis

Impurity profiling and identification

Reference standard qualification

Stability-indicating method support

Method development and validation

Stability chambers (ICH conditions)

Chiral Preparative HPLC Purification

Milligram to Gram scale purification with DAC column.

Metal Content Analysis

Quality Systems & Regulatory Compliance

GMP compliance

GLP compliance

QMS systems

ICH compliance

QA independent from production

Documentation systems

Environmental & Safety Systems

ZLD-enabled ETP

Fire & surveillance systems

Nitrogen generation system

Controlled manufacturing environment

Clean rooms

Global Reach & Export Capability

API/intermediate exports

International customer support

Integrated Team Structure

Aral Research with scientific project execution

Khodiyar Chemicals with scale-up & manufacturing

Combined chemistry and manufacturing expertise

Contract Manufacturing Support

non-GMP manufacturing

GMP manufacturing

Tech transfer

Pilot batches

Scale-up support

Commercial manufacturing

Advantage of Integrated Model

A single, accountable partner from first molecule to final API shipment — with the chemistry depth, manufacturing scale, and regulatory capability to match any program stage.
Discovery-to-commercial support 

Strong chemistry expertise

Mg to kg scale

Fast turnaround

GMP/non-GMP capability 

Scale-up expertise

Process chemistry support 

Dedicated project management 
Confidentiality 
Global delivery capability

Science ✦ Research ✦ Innovation ✦ Chemistry ✦

Our Testimonials

What our valued clients and collaborators have to say

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Parag Chaudhari profile picture
Parag Chaudhari
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Excellent experience with Aral Research Private Limited. Their team was very professional, responsive, and quick throughout the process. I had requested HPLC analysis, and everything was handled smoothly from quotation to documentation and reporting. Special thanks to Ashik from the team, who was extremely prompt in handling my request, coordinating the process, and providing timely updates. The response time and support were much better than expected. Overall, I had a very good experience with their analytical testing service and would definitely recommend Aral Research for anyone looking for reliable laboratory analysis services.
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Sahil Chandnani
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Dabhi Haresh
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Nirav Boghara
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Pravin Rajgor
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Parth Aghera
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Deepkumar Ghaghra
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Zalabhikhabhai Dhirubhai
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👍🏻
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Ekta Godhasara
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Makwana Meet
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