LCMS Analysis


LCMS Analysis Services

Aral Research is renowned for offering the highest quality Liquid Chromatography-Mass Spectrometry analysis services, tailored specially to cater to the unique requirements of different industries. Our Liquid Chromatography -Mass Spectrometry services boast unmatched accuracy and precision, making it the go-to choose of clients looking to identify and quantify compounds in a sample of interest. At Aral Research, our data interpretation and analysis expertise, backed by our highly knowledgeable and experienced analytical team, ensures our clients get the most comprehensive and accurate results. Our team is well-versed in the field of Liquid Chromatography-Mass Spectrometry analysis in myriad fields, such as pharmaceutical, nutraceuticals, biotechnology, API and Chemical analysis.


Liquid Chromatography-Mass Spectrometry is a versatile technique, suitable for systematically separating and analysing the compound by mass to charge ratio in the sample of interest. It excels at splitting complicated compounds and identifying unfamiliar chemical species. Along with its high sensitivity, LCMS analysis is renowned in various industries ranging from pharmaceutical, food & beverages, environmental analysis, proteomics and metabolomics. At Aral Research, we offer comprehensive LCMS analysis. We have Water’s Acquity UPLC (Ultra Performance Liquid Chromatography) equipped with an SQ detector to ensure high qualitative data. Our LC-MS services include mass identification, Quantification, validation and method development of critical samples.

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Mass Analysis With Aral Research

Aral Research is a trustworthy Liquid Chromatography Mass Spectrometry lab with years of hands-on experience with various novel and approved drugs. Our LCMS services resolve substances from complex biological matrices, quantitative evaluation, and impurity identification. It is a powerful analytical tool that combines the separation ability of HPLC (High-Pressure Liquid Chromatography) and mass analysis of Mass Spectrometry to offer sensitive and specific detection of different molecules.

We employ state-of-the-art techniques, fast turnaround time, custom service and clear, concise written reports to help clients resolve analytical and technical challenges. Our core focus is assisting in accomplishing analytical goals and accelerating the research timeline. With Aral Research, we bring to the table scientific experience, operational excellence and regulatory expertise to ensure your costs and resources are optimised.

Liquid Chromatography-Mass Spectrometry is an indispensable method for qualitative and qualitative analysis in a wide range of fields right, from pharmaceutical and forensic science to environmental science. At Aral Research, we take pride in our years of experience in Liquid Chromatography-Mass Spectrometry analysis for solving different characterization requirements and resolving problems. Our teams of experts use modern instruments like UPLC (Ultra Performance Liquid Chromatography) interfaced with mass spectrometer analyzers. We strive to empower researchers to identify and quantify proteins and metabolites in complex matrix, expanding the horizons of modern analytical chemistry. We have the expertise and knowledge to help you resolve analytical questions using LCMS analysis.

Why Choose Our LCMS Analysis Services?

LCMS Analysis in Pharmaceuticals

It determines pharmaceutical compounds and separates active drugs. Liquid Chromatography-Mass Spectrometry is also widely used in detecting, isolating, and purifying drug metabolites.

LCMS Analysis in Biomedical

The Liquid Chromatography-Mass Spectrometry method is helpful in the detection of steroid drugs in blood and in profiling endogenous steroids.

LCMS Analysis in Environmental Monitoring

It analyses various environmental samples such as air, drinking water, waste, and sludge. Herbicides and pesticides like chlorophenols, triazine derivatives, and sulfonylurea herbicides are analyzed, and organometallic compounds and polycyclic aromatic hydrocarbons are separated.

LCMS Analysis in Drug Detection

It is used in drug monitoring for immunosuppressants like cyclosporin, mycophenolic acid, sirolimus tacrolimus, and everolimus.


Have any questions?

Frequently Asked Questions


Liquid Chromatography- Mass Spectrometry is a powerful analytical technique typically used for drug analysis, environmental testing and food testing. It is a versatile, sensitive and specific technique for chemical analysis. This method is backed by liquid chromatography’s physical separation ability and mass spectrometry’s mass analysis. It is renowned for analyzing a range of compounds, from small molecules to proteins.

In an LCMS lab, the following types of sample matrices can be analyzed:

  • Drug formulation prepared in vitro or vito testing
  • Aqueous solutions and solvents
  • Biological fluids & tissues that are quantified for drug substances
  • Metabolites & Biomakers
  • Blood
  • Plasma
  • Tissue homogenates
  • Serum
  • Translucent matrices
  • Cell lysates

LCMS is a powerful analytical method used to identify, quantify and characterize even complex matrices of compounds. It is used in various fields like biotechnology, pharmaceuticals, forensic science, and food testing. It has a prominent application in the pharmaceutical industry as it provides a valuable aid in drug discovery and development. It is crucial assistance in metabolite identification and pharmacokinetic analysis, offering comprehensive and accurate results.

The LCMS analysis works in a two-way process. The first is liquid chromatography (LC), which involves separating the sample of interest based on chemical properties, size, charge and polarity. The second step, mass spectrometry, adds analytical expertise. The separated compounds are ionized and later separated as per their mass-to-charge ratio. This combination allows the separation and analysis of even the most complex compounds.

LCMS employs an HPCL unit along with mass spectrometry. In contrast, LCMS/MS or tandem mass spectrometry is backed with two spectrometry detectors. It allows for multiple ionizations, and when used in one ionisation event, LCMS/MS won't get the desired results.

The test validation confirms that the process employed for a specific analytical test is ideal for its intended purpose. The concerned authorities, such as FSSAI and FDA, check the full method validation for every sample matrix, analyst, and test article before regulating the sample analysis.

Usually, triple-quadrupole mass spectrometers are used for analytical and bioanalytical for quantitative small molecules because of their selectivity and sensitivity. Time-of-flight (TOF) and OTrap are used in qualitative applications. Laser Desorption mass spectrometers are used to analyze large biomolecules.

What our client have to say


K. K. Dokania WordPress Dev.

Aral Research committed to providing with the highest level of service and qualitative analytical data to our client. Our team of experts takes pride in staying up to date with the latest techniques and methodologies, and we are dedicated to providing innovative and efficient analytical solutions to meet your research needs.

Amelia Ava WordPress Dev.

ARAL RESEARCH provide qualitative analytical data with proper interpretation to help you with your research needs. We specialize in characterization reports that utilize various analytical techniques such as Mass, LCMS, HPLC, and NMR. We are proud to offer customized reports tailored to your specific research requirements.